Protein Engineering Folding and Design
The following 18 faculty members are pursuing research related to this topic.
Bezanilla, Francisco - ProfessorBiophysics and dynamics of ion channels
Dawson, Glyn - ProfessorLipid signalling pathways and progrd cell death in brain and tumors; inherited lysosomal storage diseases.
Feder, Martin E - ProfessorEvolutionary and ecological functional genomics, with Hsp70 and other molecular chaperones in Drosophila as a focus.
Getz, Godfrey S - ProfessorStructure and function of apolipoproteins in lipoprotein assembly, and in atherosclerosis and Alzheimers disease pathogenesis.
Glick, Benjamin S - ProfessorBiogenesis of secretory pathway organelles in yeast and mammalian cells, and directed evolution of fluorescent proteins.
Greene, Geoffrey L - ProfessorSteroid hormone regulation of gene networks in reproductive tissues and cancers. Structure and function of nuclear receptors.
Keenan, Robert J - Assistant ProfessorStructural biology and directed evolution.
Kent, Stephen B.H. - ProfessorApplication of chemistry to the study of proteins. Chemical protein synthesis. Protein mass spectrometry. Functional Proteomics. Mechanism of enzyme catalysis.
Koide, Shohei - Associate ProfessorProtein engineering and design. Peptide self-assembly mechanism and folding. Structural biology of signaling proteins. NMR spectroscopy.
Kossiakoff, Anthony A - ProfessorStructure and function of hormone-receptor interactions, enzyme-inhibitor interfaces, and synthetic proteins.
Makinen, Marvin W - ProfessorElectron magnetic resonance; enzyme mechanisms; metalloenzymes; molecular dynamics; structural basis of enzyme action.
Meredith, Stephen C - ProfessorProtein aggregation and amyloid fibril structure; peptide synthesis; lipoprotein structure.
Moffat, Keith - ProfessorSynchrotron radiation; time-resolved macromolecular crystallography; light-sensitive proteins
Nash, Piers - Assistant ProfessorModular protein interaction domains in signal transduction and the cell cycle.
Perozo, Eduardo - ProfessorStructure and Dynamics of Ion Channels and transporters
Rock, Ronald S - Assistant ProfessorMolecular motors; cytoskeletal organization; single-molecule biophysics
Roux, Benoit - ProfessorTheoretical and computational studies of the structure, dynamics and function of biological macromolecular systems.
Sosnick, Tobin R - ProfessorProtein and RNA/ribozyme folding; biological structure and thermodynamics as basis for understanding function.