Gene Expression and Regulation
The following 52 faculty members are pursuing research related to this topic.
Bell, Graeme I - ProfessorGenetics of diabetes and other metabolic disorders; development and regeneration of insulin-secreting pancreatic beta cells
Borevitz, Justin O - Assistant ProfessorQuantitative and population genetics of local native plant species
Crosson, Sean - Assistant ProfessorDeciphering the Structure, Function, and Topology of Microbial Signaling Systems
Du, Wei - Associate ProfessorCell cycle, tumor suppressor genes, and development.
Feder, Martin E - ProfessorEvolutionary and ecological functional genomics, with Hsp70 and other molecular chaperones in Drosophila as a focus.
Fehon, Richard - ProfessorRegulation of epithelial polarity and proliferation during development.
Gilad, Yoav - Assistant ProfessorEvolution of gene expression in primates; Evolution of the sense of smell.
Greene, Geoffrey L - ProfessorSteroid hormone regulation of gene networks in reproductive tissues and cancers. Structure and function of nuclear receptors.
Grove, Elizabeth A - ProfessorCellular and molecular mechanisms that control patterning, cell fate choice, and differentiation in the mammalian forebrain.
Haselkorn, Robert - ProfessorCellular differentiation in nitrogen-fixing cyanobacteria; acetyl CoA carboxylase in plants and humans and parasites.
He, Tong-Chuan - Associate ProfessorMolecular biology of bone and soft tissue tumors; BMP and Wnt signaling in stem cells; Regulation of mesenchymal stem cell differentiation; Cancer microenvironment and bone metastasis; Gene therapy and regenerative medicine.
Ho, Robert K - ProfessorPattern formation and early development in the simple vertebrate zebrafish.
Holaska, James M. - Assistant ProfessorRegulation of gene expression, chromatin dynamics and nuclear architecture by nuclear envelope proteins: Implications for muscular dystrophy, heart disease and aging.
Jones, Richard B - Assistant ProfessorSystems-Level Analyses of Cancer Signaling
Kee, Barbara L - Associate ProfessorTranscriptional regulation of lymphocyte development.
Kron, Stephen J - Associate ProfessorSignal transduction, cell cycle control, and checkpoints. Technology for proteomics, drug discovery and systems biology.
Lahn, Bruce - ProfessorEpigenetic Mechanisms of Cell Fate Restriction in Stem Cell Differentiation.
Lamppa, Gayle K - Associate ProfessorChloroplast development; nuclear genes coding for chloroplast proteins; regulation of protein import and posttranslational processing.
Leber, Jess - Assistant ProfessorMy research investigates the mechanisms by which mammalian innate immunity recognizes intracellular infection, and the counter-measures used by intracellular pathogens to subvert host defenses.
Liu, Chun-Yu - Assistant ProfessorGenetics/genomics underlying neuropsychiatric disorders and brain functions.
Lowe, Christopher J - Assistant ProfessorEvolution and development of deuterostomes.
Lussier, Yves A - Associate ProfessorFocus is on the use of computational systems biology and bioinformatics to accurately individualize the understanding, the prediction, and the treatment of disease.
Macleod, Kay F - Assistant ProfessorRegulation of cell cycle checkpoints and cell death in response to oxidative stress and DNA damage.
Mahowald, Anthony P - ProfessorDevelopmental genetics of oogenesis; ovarian germline stem cell; genetics of spermatogenesis.
Malamy, Jocelyn E. - Associate ProfessorMolecular regulation of root system growth and development in Arabidopsis and crop plants.
Martin, Terence E - ProfessorStructure of cell nucleus; RNA transcription and processing; implications for the immune system; novel growth factors for tissue maintenance and differentiation.
McLeod, Rima - ProfessorImmunobiology of toxoplasmosis.
Mets, Laurens - Associate ProfessorChloroplast biogenesis and genetics; biochemical genetics and photophysics of photosynthesis; correlated genomic and genetic analysis.
Millen, Kathleen - Associate ProfessorGenetic analysis vertebrate CNS development and the genetic basis of mental retardation and autism
Nobrega, Marcelo A - Assistant ProfessorGenetics of heart development and congenital heart diseases. Genetic engineering of mouse models of human diseases. Genomic organization and gene regulatory architecture. Vertebrate comparative genomics.
Olopade, Olufunmilayo (Funmi) F - ProfessorCancer genetics and epigenetics, molecular genetics of breast and ovarian cancer; genetics of cancer predisposition in diverse populations including BRCA1 and BRCA2 genes, inflammation and cancer.
Palmer, Abraham A - Assistant ProfessorGenetic basis of animal behavior, quantitative trait mapping, drug abuse and psychiatric phenotypes, translation of genetic findings to human populations
Pan, Tao - ProfessorRNA genomics, RNA epigenetics, RNA folding
Popko, Brian - ProfessorMouse models in the study of neurological disorders.
Preuss, Daphne - ProfessorGenetic analysis of fertilization in Arabidopsis reproduction. Structure and function of plant centromeres.
Ragsdale, Clifton - Associate ProfessorMolecular and cellular mechanisms of brain development
Rebay, Ilaria - Associate ProfessorTranscriptional regulatory circuitries in development and disease; Receptor tyrosine kinase signal transduction.
Refetoff, Samuel - ProfessorMolecular basis of inherited thyroid diseases.
Rinker-Schaeffer, Carrie - Associate ProfessorMolecular and mechanisims regulating cancer cell colonization of metastatic sites. Our work includes the areas of signal transduction, stress kinase activation, cell cycle progression, and novel mechanisms regulating metastatic growth including quorum sensing.
Rothman-Denes, Lucia B - ProfessorRNA polymerases structure and function; mechanisms of transcription regulation; host-viral interactions.
Rowley, Janet D - ProfessorChanges in gene expression in human leukemia cells with recurring chromosome translocations
Ruvinsky, llya - Assistant ProfessorEvolution of development, particularly the evolution of transcriptional regulation (using C. elegans as a primary model organism); Comparative and computational genomics; Molecular evolution
Schmidt-Ott, Urs - Assistant ProfessorDevelopmental Genetics and Evolution.
Schwartz, Nancy B - ProfessorTranscriptional control of ECM expression during chondrogenesis and neurogenesis; regulation of sulfate activation; skeletal dysplasias.
Shapiro, James A - ProfessorGenome reorganization and multicellular regulatory systems in bacteria populations.
Singh, Harinder - ProfessorGene regulatory networks and the specification of cell fates in the immune system. Genetic engineering of stem cells.
Staley, Jonathan P - Associate ProfessorPre-mRNA splicing: quality control, signal transduction, intron function and snRNA function. Approaches include genetics, genomics, cell biology and biochemistry in budding yeast.
Storb, Ursula - ProfessorImmunoglobulin gene expression; somatic hypermutation; regulation and functions of DNA methylation and chromatin modifications in development and transcription.
Svensson, Eric - Associate ProfessorDevelopmental biology of the cardiovascular system with emphasis on the transcriptional regulation of cardiac development
Turkewitz, Aaron - Associate ProfessorSecretory granules; exocytosis and endocytosis; evolution of membrane traffic.
White, Kevin P - ProfessorThe White lab studies the coordinated action of networks of genes that control developmental processes.
Wool, Ira G - ProfessorStructure and function of eukaryotic ribosomes; RNA structures; RNA-protein interaction.