Structural and Computational Biology
The following 19 faculty members are pursuing research related to this topic.
Adams, Erin J - Assistant ProfessorStructure and biochemistry of proteins involved in immunological recognition. Characterization of gamma delta T cell receptors and their ligands and activating and inhibitory receptors involved in the innate immune response.
Crosson, Sean - Assistant ProfessorDeciphering the Structure, Function, and Topology of Microbial Signaling Systems
Glick, Benjamin S - ProfessorBiogenesis of secretory pathway organelles in yeast and mammalian cells, and directed evolution of fluorescent proteins.
Greene, Geoffrey L - ProfessorSteroid hormone regulation of gene networks in reproductive tissues and cancers. Structure and function of nuclear receptors.
Gupta, Mohan L - Assistant Professor Mechanisms that regulate microtubule functions / interactions; roles of motor proteins in controlling microtubule dynamics; approaches range from in-vivo live cell imaging and functional assays to in-vitro single molecule analysis.
Josephs, Robert - ProfessorStructure of sickle-cell hemoglobin fibers and the red cell cytoskeleton by cryoelectron microscopy and image reconstruction.
Keenan, Robert J - Assistant ProfessorStructural biology and directed evolution.
Kent, Stephen B.H. - ProfessorApplication of chemistry to the study of proteins. Chemical protein synthesis. Protein mass spectrometry. Functional Proteomics. Mechanism of enzyme catalysis.
Koide, Shohei - Associate ProfessorProtein engineering and design. Peptide self-assembly mechanism and folding. Structural biology of signaling proteins. NMR spectroscopy.
Kossiakoff, Anthony A - ProfessorStructure and function of hormone-receptor interactions, enzyme-inhibitor interfaces, and synthetic proteins.
Liu, Chun-Yu - Assistant ProfessorGenetics/genomics underlying neuropsychiatric disorders and brain functions.
Makinen, Marvin W - ProfessorElectron magnetic resonance; enzyme mechanisms; metalloenzymes; molecular dynamics; structural basis of enzyme action.
Moffat, Keith - ProfessorSynchrotron radiation; time-resolved macromolecular crystallography; light-sensitive proteins
Nash, Piers - Assistant ProfessorModular protein interaction domains in signal transduction and the cell cycle.
Perozo, Eduardo - ProfessorStructure and Dynamics of Ion Channels and transporters
Rice, Phoebe A - Associate ProfessorWe study mechanisms of DNA recombination and protein-DNA recognition, combining the tools of biochemistry and x-ray crystallography.
Roux, Benoit - ProfessorTheoretical and computational studies of the structure, dynamics and function of biological macromolecular systems.
Rzhetsky, Andrey - ProfessorAnalysis of complex molecular networks for understanding common phenotypes
Sosnick, Tobin R - ProfessorProtein and RNA/ribozyme folding; biological structure and thermodynamics as basis for understanding function.