Cancer Genetics
The following 26 faculty members are pursuing research related to this topic.
Bishop, Douglas K - ProfessorMeiotic recombination, recombinational DNA repair in yeast and mammalian cells.
Cunningham, John - ProfessorBiology and therapy of hemoglobinopathies, developmental biology of blood and neural crest, and stem cell research.
Das, Soma - Associate ProfessorMolecular diagnostics of genetic disease.
Di Rienzo, Anna - ProfessorHuman genetic variation and the evolution of common diseases.
Dolan, M. Eileen - ProfessorPharmacogenomics of Anticancer Agents
Du, Wei - Associate ProfessorCell cycle, tumor suppressor genes, and development.
Ellis, Nathan Ames - Associate ProfessorMolecular mechanisms that maintain genomic integrity, with special emphasis on the RecQ helicases; the genetics colon cancer susceptibility.
Fehon, Richard - ProfessorRegulation of epithelial polarity and proliferation during development.
He, Tong-Chuan - Associate ProfessorMolecular biology of bone and soft tissue tumors; BMP and Wnt signaling in stem cells; Regulation of mesenchymal stem cell differentiation; Cancer microenvironment and bone metastasis; Gene therapy and regenerative medicine.
Imamoto, Akira - Associate ProfessorMouse models of human syndromes affecting morphogenesis, patterning, and cell fate during craniofacial and cardiovascular development.
Jones, Richard B - Assistant ProfessorSystems-Level Analyses of Cancer Signaling
Kee, Barbara L - Associate ProfessorTranscriptional regulation of lymphocyte development.
Kron, Stephen J - Associate ProfessorSignal transduction, cell cycle control, and checkpoints. Technology for proteomics, drug discovery and systems biology.
Lahn, Bruce - ProfessorEpigenetic Mechanisms of Cell Fate Restriction in Stem Cell Differentiation.
Le Beau, Michelle M - ProfessorMolecular analysis of recurring chromosomal abnormalities in human tumors; identification of cooperating mutations and genetic pathways leading to transformation.
Macleod, Kay F - Assistant ProfessorRegulation of cell cycle checkpoints and cell death in response to oxidative stress and DNA damage.
Nobrega, Marcelo A - Assistant ProfessorGenetics of heart development and congenital heart diseases. Genetic engineering of mouse models of human diseases. Genomic organization and gene regulatory architecture. Vertebrate comparative genomics.
Olopade, Olufunmilayo (Funmi) F - ProfessorCancer genetics and epigenetics, molecular genetics of breast and ovarian cancer; genetics of cancer predisposition in diverse populations including BRCA1 and BRCA2 genes, inflammation and cancer.
Rebay, Ilaria - Associate ProfessorTranscriptional regulatory circuitries in development and disease; Receptor tyrosine kinase signal transduction.
Rowley, Janet D - ProfessorChanges in gene expression in human leukemia cells with recurring chromosome translocations
Rzhetsky, Andrey - ProfessorAnalysis of complex molecular networks for understanding common phenotypes
Skapek, Stephen - Associate ProfessorFunctional analysis of cancer suppressing genes.
Staley, Jonathan P - Associate ProfessorPre-mRNA splicing: quality control, signal transduction, intron function and snRNA function. Approaches include genetics, genomics, cell biology and biochemistry in budding yeast.
Storb, Ursula - ProfessorImmunoglobulin gene expression; somatic hypermutation; regulation and functions of DNA methylation and chromatin modifications in development and transcription.
Strauss, Bernard S - ProfessorMechanism of mutation; role of DNA polymerases in response to mutagenic agents.
White, Kevin P - ProfessorThe White lab studies the coordinated action of networks of genes that control developmental processes.