Cell Signaling
The following 33 faculty members are pursuing research related to this topic.
Bell, Graeme I - ProfessorGenetics of diabetes and other metabolic disorders; development and regeneration of insulin-secreting pancreatic beta cells
Crosson, Sean - Assistant ProfessorDeciphering the Structure, Function, and Topology of Microbial Signaling Systems
Dawson, Glyn - ProfessorLipid signalling pathways and progrd cell death in brain and tumors; inherited lysosomal storage diseases.
Du, Wei - Associate ProfessorCell cycle, tumor suppressor genes, and development.
Fehon, Richard - ProfessorRegulation of epithelial polarity and proliferation during development.
Ferguson, Edwin L - ProfessorDevelopmental genetics of cell fate specification and stem cell maintenance in Drosophila
Glotzer, Michael - Associate ProfessorThe molecular mechanism of cytokinesis in animal cells
Greenberg, Jean T - ProfessorArabidopsis defense mechanisms against bacterial infection; Pseudomonas syringae virulence mechanisms.
Greene, Geoffrey L - ProfessorSteroid hormone regulation of gene networks in reproductive tissues and cancers. Structure and function of nuclear receptors.
Haselkorn, Robert - ProfessorCellular differentiation in nitrogen-fixing cyanobacteria; acetyl CoA carboxylase in plants and humans and parasites.
He, Tong-Chuan - Associate ProfessorMolecular biology of bone and soft tissue tumors; BMP and Wnt signaling in stem cells; Regulation of mesenchymal stem cell differentiation; Cancer microenvironment and bone metastasis; Gene therapy and regenerative medicine.
Ho, Robert K - ProfessorPattern formation and early development in the simple vertebrate zebrafish.
Holaska, James M. - Assistant ProfessorRegulation of gene expression, chromatin dynamics and nuclear architecture by nuclear envelope proteins: Implications for muscular dystrophy, heart disease and aging.
Horne-Badovinac, Sally - Assistant ProfessorEpithelial morphogenesis and organ shape
Jones, Richard B - Assistant ProfessorSystems-Level Analyses of Cancer Signaling
Kay, Brian - ProfessorMapping protein-protein interactions with combinatorial peptides, engineered proteins, and phage-display
Koide, Shohei - Associate ProfessorProtein engineering and design. Peptide self-assembly mechanism and folding. Structural biology of signaling proteins. NMR spectroscopy.
Kossiakoff, Anthony A - ProfessorStructure and function of hormone-receptor interactions, enzyme-inhibitor interfaces, and synthetic proteins.
Kron, Stephen J - Associate ProfessorSignal transduction, cell cycle control, and checkpoints. Technology for proteomics, drug discovery and systems biology.
Leber, Jess - Assistant ProfessorMy research investigates the mechanisms by which mammalian innate immunity recognizes intracellular infection, and the counter-measures used by intracellular pathogens to subvert host defenses.
Macleod, Kay F - Assistant ProfessorRegulation of cell cycle checkpoints and cell death in response to oxidative stress and DNA damage.
Mahowald, Anthony P - ProfessorDevelopmental genetics of oogenesis; ovarian germline stem cell; genetics of spermatogenesis.
Nash, Piers - Assistant ProfessorModular protein interaction domains in signal transduction and the cell cycle.
Popko, Brian - ProfessorMouse models in the study of neurological disorders.
Preuss, Daphne - ProfessorGenetic analysis of fertilization in Arabidopsis reproduction. Structure and function of plant centromeres.
Ragsdale, Clifton - Associate ProfessorMolecular and cellular mechanisms of brain development
Rebay, Ilaria - Associate ProfessorTranscriptional regulatory circuitries in development and disease; Receptor tyrosine kinase signal transduction.
Rinker-Schaeffer, Carrie - Associate ProfessorMolecular and mechanisims regulating cancer cell colonization of metastatic sites. Our work includes the areas of signal transduction, stress kinase activation, cell cycle progression, and novel mechanisms regulating metastatic growth including quorum sensing.
Rosner, Marsha R - ProfessorGrowth factor receptor signaling leading to cell growth, cell differentiation or cell death.
Roux, Benoit - ProfessorTheoretical and computational studies of the structure, dynamics and function of biological macromolecular systems.
Rzhetsky, Andrey - ProfessorAnalysis of complex molecular networks for understanding common phenotypes
Shapiro, James A - ProfessorGenome reorganization and multicellular regulatory systems in bacteria populations.
Staley, Jonathan P - Associate ProfessorPre-mRNA splicing: quality control, signal transduction, intron function and snRNA function. Approaches include genetics, genomics, cell biology and biochemistry in budding yeast.